InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Sult1a1

Summary

InnateDB Gene

IDBG-209709.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sult1a1

Gene Name

sulfotransferase family 1A, phenol-preferring, member 1

Synonyms

AI266890; PST; ST1A1; Stp; Stp1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000030711

Encoded Proteins

IDBP-268902

sulfotransferase family 1A, phenol-preferring, member 1

IDBP-268904

sulfotransferase family 1A, phenol-preferring, member 1

IDBP-268906

sulfotransferase family 1A, phenol-preferring, member 1

IDBP-533891

sulfotransferase family 1A, phenol-preferring, member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196502:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:126672865-126676432

Strand

Reverse strand

Band

Transcripts

ENSMUST00000106373	ENSMUSP00000101981
ENSMUST00000106372	ENSMUSP00000101980
ENSMUST00000106371	ENSMUSP00000101979
ENSMUST00000155419	ENSMUSP00000121514

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.

Predicted by orthology
Total	35 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004062	aryl sulfotransferase activity
GO:0008146	sulfotransferase activity
GO:0042803	protein homodimerization activity
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding

Biological Process

GO:0006584	catecholamine metabolic process
GO:0006805	xenobiotic metabolic process
GO:0008152	metabolic process
GO:0008210	estrogen metabolic process
GO:0008217	regulation of blood pressure
GO:0014823	response to activity
GO:0017085	response to insecticide
GO:0018960	4-nitrophenol metabolic process
GO:0051384	response to glucocorticoid
GO:0051923	sulfation