Version 5.4
Mus musculus Gene: Rbbp6
Summary
InnateDB Gene IDBG-209019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rbbp6
Gene Name retinoblastoma binding protein 6
Synonyms 4933422O15Rik; AI316869; BB233631; C030034J04Rik; C77662; P2P-R; PACT
Species Mus musculus
Ensembl Gene ENSMUSG00000030779
Encoded Proteins
IDBP-209012
retinoblastoma binding protein 6
IDBP-209021
retinoblastoma binding protein 6
IDBP-209023
retinoblastoma binding protein 6
IDBP-538841
retinoblastoma binding protein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122257:
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:122965686-123002557
Strand Forward strand
Band F2
Transcripts
ENSMUST00000098062 ENSMUSP00000095670
ENSMUST00000071590 ENSMUSP00000071519
ENSMUST00000052135 ENSMUSP00000049528
ENSMUST00000148880 ENSMUSP00000115530
ENSMUST00000137860
ENSMUST00000156738
ENSMUST00000126053
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 44 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001701 in utero embryonic development
GO:0016567 protein ubiquitination
GO:0035264 multicellular organism growth
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0048568 embryonic organ development
GO:0061053 somite development
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000122257
View Gene Order
ENSBTAG00000009441
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.394197 Mm.4480
RefSeq NM_011247 NM_175023 XM_006507470
OMIM
CCDS CCDS21817 CCDS52387
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca