Version 5.4
Mus musculus Gene: Daglb
Summary
InnateDB Gene IDBG-207742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Daglb
Gene Name diacylglycerol lipase, beta
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039206
Encoded Proteins
IDBP-207744
diacylglycerol lipase, beta
IDBP-542969
diacylglycerol lipase, beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23103940
DAGLB is a key metabolic hub within a lipid network that regulates proinflammatory responses in peritoneal macrophages.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164535:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:143464493-143504442
Strand Forward strand
Band G2
Transcripts
ENSMUST00000045593 ENSMUSP00000043088
ENSMUST00000145651 ENSMUSP00000119765
ENSMUST00000155383
ENSMUST00000174273
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004806 triglyceride lipase activity
GO:0046872 metal ion binding
Biological Process
GO:0006629 lipid metabolic process
GO:0007405 neuroblast proliferation
GO:0016042 lipid catabolic process
GO:0019369 arachidonic acid metabolic process
GO:0022008 neurogenesis
GO:0042136 neurotransmitter biosynthetic process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164535
View Gene Order
ENSBTAG00000009236
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_224553
Hemostasis pathway
REACT_254215
Signaling by GPCR pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_247231
Arachidonate production from DAG pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_219232
Effects of PIP2 hydrolysis pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19308
Arachidonate production from DAG pathway
REACT_2202
Effects of PIP2 hydrolysis pathway
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14797
Signaling by GPCR pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 231871
UniGene Mm.417181
RefSeq XM_006504699 XM_006504700 NM_144915
OMIM
CCDS CCDS39370
HPRD
IMGT
MGI ID MGI:2442032
MGI Symbol Daglb
EMBL
GenPept
RNA Seq Atlas 231871

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca