Version 5.4
Mus musculus Gene: Fam20c
Summary
InnateDB Gene IDBG-206300.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam20c
Gene Name family with sequence similarity 20, member C
Synonyms C76981; DMP-4; DMP4; GEF-CK; mKIAA4081
Species Mus musculus
Ensembl Gene ENSMUSG00000025854
Encoded Proteins
IDBP-206302
family with sequence similarity 20, member C
IDBP-537228
family with sequence similarity 20, member C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177706:
This gene encodes a member of the family with sequence similarity 20 (FAM20) family of secreted proteins. A similar gene in mice encodes a protein that plays a role in dentin mineralization, and mutations in the human gene are associated with the autosomal recessive disorder Raine syndrome. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:138754514-138810077
Strand Forward strand
Band G2
Transcripts
ENSMUST00000026972 ENSMUSP00000026972
ENSMUST00000160645 ENSMUSP00000124584
ENSMUST00000159176
ENSMUST00000160988
ENSMUST00000161641
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004674 protein serine/threonine kinase activity
GO:0005509 calcium ion binding
Biological Process
GO:0001501 skeletal system development
GO:0006468 protein phosphorylation
GO:0030501 positive regulation of bone mineralization
GO:0036179 osteoclast maturation
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway
GO:0045669 positive regulation of osteoblast differentiation
GO:0051174 regulation of phosphorus metabolic process
GO:0070166 enamel mineralization
GO:0071895 odontoblast differentiation
GO:0097187 dentinogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000177706
View Gene Order
ENSBTAG00000003607
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_030565 XM_006504775
OMIM
CCDS CCDS51681
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca