Mus musculus Gene: Chrm5
Summary
InnateDB Gene IDBG-196720.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chrm5
Gene Name cholinergic receptor, muscarinic 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000074939
Encoded Proteins
cholinergic receptor, muscarinic 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184984:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:112479171-112480769
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000099589 ENSMUSP00000097185
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0016907 G-protein coupled acetylcholine receptor activity
GO:0016934 extracellular-glycine-gated chloride channel activity
Biological Process
GO:0001696 gastric acid secretion
GO:0006821 chloride transport
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007213 G-protein coupled acetylcholine receptor signaling pathway
GO:0015872 dopamine transport
GO:0019226 transmission of nerve impulse
GO:0060304 regulation of phosphatidylinositol dephosphorylation
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Amine ligand-binding receptors pathway
Muscarinic acetylcholine receptors pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
KEGG
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
Regulation of actin cytoskeleton pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Muscarinic acetylcholine receptors pathway
Amine ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Regulation of actin cytoskeleton pathway
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q920H4
TrEMBL
UniProt Splice Variant
Entrez Gene 213788
UniGene Mm.297624
RefSeq NM_205783 XM_006499099
OMIM
CCDS CCDS16556
HPRD
IMGT
MGI ID MGI:109248
MGI Symbol Chrm5
EMBL AF264051 AL731840 BC120615
GenPept AAI20616 AAL26028 CAM25807
RNA Seq Atlas 213788