Version 5.4
Mus musculus Gene: Lipc
Summary
InnateDB Gene IDBG-182685.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lipc
Gene Name lipase, hepatic
Synonyms AI256194; HL; Hpl
Species Mus musculus
Ensembl Gene ENSMUSG00000032207
Encoded Proteins
IDBP-182687
lipase, hepatic
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166035:
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:70798129-70934808
Strand Reverse strand
Band D
Transcripts
ENSMUST00000034731 ENSMUSP00000034731
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004806 triglyceride lipase activity
GO:0005515 protein binding
GO:0008201 heparin binding
GO:0016298 lipase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0008203 cholesterol metabolic process
GO:0019433 triglyceride catabolic process
GO:0030301 cholesterol transport
GO:0034372 very-low-density lipoprotein particle remodeling
GO:0034374 low-density lipoprotein particle remodeling
GO:0034375 high-density lipoprotein particle remodeling
GO:0042632 cholesterol homeostasis
GO:0070328 triglyceride homeostasis
Cellular Component
GO:0005615 extracellular space
GO:0034364 high-density lipoprotein particle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166035
View Gene Order
ENSBTAG00000005479
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00561
Glycerolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.390187
RefSeq NM_008280
OMIM
CCDS CCDS23324
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca