Version 5.4
Mus musculus Gene: Brpf1
Summary
InnateDB Gene IDBG-176213.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brpf1
Gene Name bromodomain and PHD finger containing, 1
Synonyms 4833438B11Rik; 4930540D11Rik; Brpf2
Species Mus musculus
Ensembl Gene ENSMUSG00000001632
Encoded Proteins
IDBP-254544
bromodomain and PHD finger containing, 1
IDBP-254546
bromodomain and PHD finger containing, 1
IDBP-254548
bromodomain and PHD finger containing, 1
IDBP-254550
bromodomain and PHD finger containing, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156983:
The protein encoded by this gene is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and it is very similar in structure to two zinc finger proteins, AF10 and AF17. It is suggested that these proteins form a family of regulatory proteins. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:113307181-113324857
Strand Forward strand
Band E3
Transcripts
ENSMUST00000113122 ENSMUSP00000108747
ENSMUST00000113121 ENSMUSP00000108746
ENSMUST00000113119 ENSMUSP00000108744
ENSMUST00000113117 ENSMUSP00000108742
ENSMUST00000124530
ENSMUST00000138737
ENSMUST00000131594
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0043966 histone H3 acetylation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0070776 MOZ/MORF histone acetyltransferase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000156983
View Gene Order
ENSBTAG00000007776
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.356059 Mm.464201
RefSeq NM_001282126 NM_001282127 NM_001282128 NM_030178 XM_006506782 XM_006506783 XM_006506784 XM_006506785 XM_006506786 XM_006506787 XM_006506788
OMIM
CCDS CCDS39592 CCDS71809 CCDS71810
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca