InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ckb

Summary

InnateDB Gene

IDBG-173411.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ckb

Gene Name

creatine kinase, brain

Synonyms

B-CK; Bck; Ck-3; Ck3; Ckbb

Species

Mus musculus

Ensembl Gene

ENSMUSG00000001270

Encoded Proteins

IDBP-173413

creatine kinase, brain

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166165:
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:111669355-111672338

Strand

Reverse strand

Band

Transcripts

ENSMUST00000001304

ENSMUSP00000001304

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004111	creatine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups