Mus musculus Gene: Mapk12 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-172617.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Mapk12 | ||||||||||||||||||||||
Gene Name | mitogen-activated protein kinase 12 | ||||||||||||||||||||||
Synonyms | AW123708; Erk6; P38gamma; Prkm12; Sapk3 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000022610 | ||||||||||||||||||||||
Encoded Proteins |
mitogen-activated protein kinase 12
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188130:
Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 15:89130585-89140703 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | E3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Innate Immune System pathway
Organelle biogenesis and maintenance pathway
Signaling by VEGF pathway
Immune System pathway
Myogenesis pathway
DSCAM interactions pathway
Signalling to RAS pathway
CDO in myogenesis pathway
p38MAPK events pathway
VEGFA-VEGFR2 Pathway pathway
Signalling to ERKs pathway
NOD1/2 Signaling Pathway pathway
Signalling by NGF pathway
Developmental Biology pathway
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways pathway
NGF signalling via TRKA from the plasma membrane pathway
Signal Transduction pathway
Mitochondrial biogenesis pathway
Cell-Cell communication pathway
Activation of PPARGC1A (PGC-1alpha) by phosphorylation pathway
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KEGG |
VEGF signaling pathway pathway
T cell receptor signaling pathway pathway
Toll-like receptor signaling pathway pathway
Fc epsilon RI signaling pathway pathway
GnRH signaling pathway pathway
MAPK signaling pathway pathway
Leukocyte transendothelial migration pathway
Amyotrophic lateral sclerosis (ALS) pathway
Neurotrophin signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
RIG-I-like receptor signaling pathway pathway
NOD-like receptor signaling pathway pathway
Oocyte meiosis pathway
Leishmaniasis pathway
Osteoclast differentiation pathway
Toxoplasmosis pathway
Hepatitis C pathway
Chagas disease (American trypanosomiasis) pathway
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INOH |
IL-7 signaling pathway
IL-1 signaling pathway pathway
Toll-like receptor signaling pathway pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
BMP2 signaling pathway
TGF-beta signaling pathway
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PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
KitReceptor pathway
TSLP pathway
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REACTOME |
NOD1/2 Signaling Pathway pathway
p38MAPK events pathway
Signalling to RAS pathway
DSCAM interactions pathway
CDO in myogenesis pathway
Organelle biogenesis and maintenance pathway
Developmental Biology pathway
Signalling by NGF pathway
Cell-Cell communication pathway
Activation of PPARGC1A (PGC-1alpha) by phosphorylation pathway
Signaling by VEGF pathway
Mitochondrial biogenesis pathway
Innate Immune System pathway
Signal Transduction pathway
Myogenesis pathway
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways pathway
Immune System pathway
VEGFA-VEGFR2 Pathway pathway
Signalling to ERKs pathway
NGF signalling via TRKA from the plasma membrane pathway
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KEGG |
GnRH signaling pathway pathway
VEGF signaling pathway pathway
Fc epsilon RI signaling pathway pathway
Epithelial cell signaling in Helicobacter pylori infection pathway
MAPK signaling pathway pathway
Leukocyte transendothelial migration pathway
T cell receptor signaling pathway pathway
Toll-like receptor signaling pathway pathway
Amyotrophic lateral sclerosis (ALS) pathway
Neurotrophin signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
RIG-I-like receptor signaling pathway pathway
NOD-like receptor signaling pathway pathway
Oocyte meiosis pathway
Leishmaniasis pathway
Chagas disease (American trypanosomiasis) pathway
Osteoclast differentiation pathway
Shigellosis pathway
Toxoplasmosis pathway
Hepatitis C pathway
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INOH |
IL-7 signaling pathway
IL-1 signaling pathway pathway
Toll-like receptor signaling pathway pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
TGF-beta signaling pathway
BMP2 signaling pathway
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PID NCI |
Signaling mediated by p38-gamma and p38-delta
RhoA signaling pathway
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | |||||||||||||||||||||||
RefSeq | NM_013871 XM_006521063 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS27740 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||