Homo sapiens Gene: NUP155 | |||||||||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||||||||
InnateDB Gene | IDBG-17015.6 | ||||||||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||||
Gene Symbol | NUP155 | ||||||||||||||||||||||||||||||
Gene Name | nucleoporin 155kDa | ||||||||||||||||||||||||||||||
Synonyms | ATFB15; N155 | ||||||||||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||||||||||
Ensembl Gene | ENSG00000113569 | ||||||||||||||||||||||||||||||
Encoded Proteins |
nucleoporin 155kDa
nucleoporin 155kDa
nucleoporin 155kDa
nucleoporin 155kDa
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Protein Structure | |||||||||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||||
Summary |
Nucleoporins are the main components of the nuclear pore complex (NPC) of eukaryotic cells. They are involved in the bidirectional trafficking of molecules, especially mRNAs and proteins, between the nucleus and the cytoplasm. The protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013] |
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Gene Information | |||||||||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||||||||
Genomic Location | Chromosome 5:37288137-37371181 | ||||||||||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||||||||||
Band | p13.2 | ||||||||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||||||||
REACTOME |
ISG15 antiviral mechanism pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
Glucose transport pathway
Hexose transport pathway
Nuclear import of Rev protein pathway
Vpr-mediated nuclear import of PICs pathway
Rev-mediated nuclear export of HIV RNA pathway
Viral Messenger RNA Synthesis pathway
Late Phase of HIV Life Cycle pathway
Transmembrane transport of small molecules pathway
Influenza Infection pathway
Interactions of Vpr with host cellular proteins pathway
Myoclonic epilepsy of Lafora pathway
Antiviral mechanism by IFN-stimulated genes pathway
Cytokine Signaling in Immune system pathway
Metabolism of carbohydrates pathway
Transcriptional regulation by small RNAs pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Influenza Viral RNA Transcription and Replication pathway
Interferon Signaling pathway
Cell Cycle pathway
Immune System pathway
M Phase pathway
HIV Life Cycle pathway
Mitotic Prophase pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
Influenza Life Cycle pathway
Metabolism pathway
Host Interactions of HIV factors pathway
SLC-mediated transmembrane transport pathway
Interactions of Rev with host cellular proteins pathway
Gene Expression pathway
Nuclear Envelope Breakdown pathway
Disease pathway
Glycogen storage diseases pathway
Regulatory RNA pathways pathway
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KEGG |
RNA transport pathway
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INOH | |||||||||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||||||||
TrEMBL | D6RA13 | ||||||||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||||||||
Entrez Gene | 9631 | ||||||||||||||||||||||||||||||
UniGene | Hs.547696 Hs.633161 | ||||||||||||||||||||||||||||||
RefSeq | NM_001278312 NM_004298 NM_153485 | ||||||||||||||||||||||||||||||
HUGO | HGNC:8063 | ||||||||||||||||||||||||||||||
OMIM | 606694 | ||||||||||||||||||||||||||||||
CCDS | CCDS3921 CCDS43310 CCDS64142 | ||||||||||||||||||||||||||||||
HPRD | 05984 | ||||||||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||||||||
EMBL | AC008832 AC025449 AC117532 | ||||||||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||||||||
RNA Seq Atlas | 9631 | ||||||||||||||||||||||||||||||