Version 5.4
Mus musculus Gene: Foxn3
Summary
InnateDB Gene IDBG-163381.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxn3
Gene Name forkhead box N3
Synonyms 5430426H20Rik; AA589593; AW556347; Ches1; Ches1l; HTLFL1
Species Mus musculus
Ensembl Gene ENSMUSG00000033713
Encoded Proteins
IDBP-163383
forkhead box N3
IDBP-163385
forkhead box N3
IDBP-712403
IDBP-710432
IDBP-710734
IDBP-711790
IDBP-713299
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000053254:
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:99194980-99450111
Strand Reverse strand
Band E
Transcripts
ENSMUST00000046859 ENSMUSP00000036035
ENSMUST00000085108 ENSMUSP00000082189
ENSMUST00000176311
ENSMUST00000177269 ENSMUSP00000135814
ENSMUST00000176959 ENSMUSP00000135873
ENSMUST00000176829 ENSMUSP00000135331
ENSMUST00000177451 ENSMUSP00000135082
ENSMUST00000176928 ENSMUSP00000135749
ENSMUST00000177287
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000053254
View Gene Order
ENSBTAG00000046684
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.341972 Mm.421593
RefSeq NM_183186 XM_006516239 XM_006516240
OMIM
CCDS CCDS26103
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca