Version 5.4
Mus musculus Gene: Wdr7
Summary
InnateDB Gene IDBG-153465.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr7
Gene Name WD repeat domain 7
Synonyms AI462727; mKIAA0541; TRAG
Species Mus musculus
Ensembl Gene ENSMUSG00000040560
Encoded Proteins
IDBP-153469
WD repeat domain 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000091157:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63708695-63989760
Strand Forward strand
Band E1
Transcripts
ENSMUST00000072726 ENSMUSP00000072509
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000091157
View Gene Order
ENSBTAG00000004005
Not yet available
Cross-References
SwissProt Q920I9
TrEMBL
UniProt Splice Variant
Entrez Gene 104082
UniGene Mm.30850 Mm.490663
RefSeq NM_001014981 XM_006525478
OMIM
CCDS CCDS50307
HPRD
IMGT
MGI ID MGI:1860197
MGI Symbol Wdr7
EMBL AF188123 AF188124 AK122304 AK154451 BC125573 BC137785 CH466528
GenPept AAI25574 AAI37786 AAL03981 AAL03982 BAC65586 BAE32595 EDL09715
RNA Seq Atlas 104082

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca