Mus musculus Gene: Upp1
Summary
InnateDB Gene IDBG-149661.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Upp1
Gene Name uridine phosphorylase 1
Synonyms AI325217; UdRPase; Up; UPase; Upp
Species Mus musculus
Ensembl Gene ENSMUSG00000020407
Encoded Proteins
uridine phosphorylase 1
uridine phosphorylase 1
uridine phosphorylase 1
uridine phosphorylase 1
uridine phosphorylase 1
uridine phosphorylase 1
uridine phosphorylase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183696:
The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).[supplied by OMIM, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:9118103-9136170
Strand Forward strand
Band A1
Transcripts
ENSMUST00000020677 ENSMUSP00000020677
ENSMUST00000101525 ENSMUSP00000099063
ENSMUST00000130522 ENSMUSP00000123285
ENSMUST00000146696
ENSMUST00000170444 ENSMUSP00000125934
ENSMUST00000168121
ENSMUST00000172452 ENSMUSP00000129787
ENSMUST00000166455 ENSMUSP00000129276
ENSMUST00000164791 ENSMUSP00000127473
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004850 uridine phosphorylase activity
Biological Process
GO:0006220 pyrimidine nucleotide metabolic process
GO:0009116 nucleoside metabolic process
GO:0009166 nucleotide catabolic process
GO:0042149 cellular response to glucose starvation
GO:0044206 UMP salvage
GO:0046108 uridine metabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Pyrimidine metabolism pathway
Metabolism pathway
Pyrimidine salvage reactions pathway
Pyrimidine catabolism pathway
Metabolism of nucleotides pathway
KEGG
Pyrimidine metabolism pathway
Drug metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pyrimidine salvage reactions pathway
Pyrimidine catabolism pathway
Metabolism of nucleotides pathway
Pyrimidine metabolism pathway
Metabolism pathway
KEGG
Pyrimidine metabolism pathway
Drug metabolism pathway
INOH
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.4610
RefSeq NM_001159401 NM_001159402 NM_009477 XM_006514667
OMIM
CCDS CCDS24432
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas