Version 5.4
Mus musculus Gene: Gas2l1
Summary
InnateDB Gene IDBG-143992.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gas2l1
Gene Name growth arrest-specific 2 like 1
Synonyms 4930500E24Rik; D0Jmb1; Gar22; TU-71.1
Species Mus musculus
Ensembl Gene ENSMUSG00000034201
Encoded Proteins
IDBP-143994
growth arrest-specific 2 like 1
IDBP-143996
growth arrest-specific 2 like 1
IDBP-261423
growth arrest-specific 2 like 1
IDBP-538941
growth arrest-specific 2 like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the Gas2 family, actin-associated proteins expressed at high levels in growth-arrested cells. The gene expression is negatively regulated by serum and growth factors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:5054132-5065327
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000037146 ENSMUSP00000043709
ENSMUST00000056649 ENSMUSP00000050275
ENSMUST00000109895 ENSMUSP00000105521
ENSMUST00000122886
ENSMUST00000156196
ENSMUST00000152257 ENSMUSP00000121993
ENSMUST00000151936
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008093 cytoskeletal adaptor activity
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0001578 microtubule bundle formation
GO:0007026 negative regulation of microtubule depolymerization
GO:0007050 cell cycle arrest
GO:0009267 cellular response to starvation
GO:0010629 negative regulation of gene expression
GO:0030308 negative regulation of cell growth
GO:0045647 negative regulation of erythrocyte differentiation
GO:0051726 regulation of cell cycle
GO:0097067 cellular response to thyroid hormone stimulus
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185340
View Gene Order
ENSBTAG00000012504
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001190408 NM_030228 NM_144560
OMIM
CCDS CCDS36101 CCDS48745
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca