Version 5.4
Homo sapiens Gene: CDK13
Summary
InnateDB Gene IDBG-13277.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDK13
Gene Name cyclin-dependent kinase 13
Synonyms CDC2L; CDC2L5; CHED; hCDK13
Species Homo sapiens
Ensembl Gene ENSG00000065883
Encoded Proteins
IDBP-13279
cyclin-dependent kinase 13
IDBP-13281
cyclin-dependent kinase 13
IDBP-809253
cyclin-dependent kinase 13
IDBP-809259
cyclin-dependent kinase 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.[provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:39950037-40097134
Strand Forward strand
Band p14.1
Transcripts
ENST00000181839 ENSP00000181839
ENST00000340829 ENSP00000340557
ENST00000484589
ENST00000478563
ENST00000465643
ENST00000613626 ENSP00000480835
ENST00000611390 ENSP00000484610
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0030332 cyclin binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0006468 protein phosphorylation
GO:0007088 regulation of mitosis
GO:0007275 multicellular organismal development
GO:0008284 positive regulation of cell proliferation
GO:0016032 viral process
GO:0030097 hemopoiesis
GO:0070816 phosphorylation of RNA polymerase II C-terminal domain
Cellular Component
GO:0002945 cyclin K-CDK13 complex
GO:0005615 extracellular space
GO:0016607 nuclear speck
GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041297
View Gene Order
ENSBTAG00000001528
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.233552 Hs.596234 Hs.701006
RefSeq NM_003718 NM_031267
HUGO
OMIM
CCDS CCDS5461 CCDS5462
HPRD 04496
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca